Wine (Windows is Not Emulated) is a very cleverly engineered tool; it allows one to run Windows applications natively on Intel based Linux systems, to different degrees of success depending on what underlying Windows APIs are used by the application.
I never know what to think about using Wine. Part of me wants to just refuse to use any Windows application because it's "tainting" my system - I want to have 100% GPL'd Open Source based code running on my machine. Using this argument I should not be using apps like Skype or Flash and hence the BBC iPlayer and I should therefore refuse to use any close proprietary drivers, like the broadcom wl.ko driver module. Where does one draw the line?
Perhaps my machine should be a totally Windows free zone - that's one line I could draw. Alternatively, if I have to run Windows code, maybe it should be just inside a Virtual Machine just to contain it, rather than using apps in Wine.
It's a interesting debate - my current approach is go for as much GPL'd Open Source code I can, and be pragmatic - use some propriety apps like Skype only when I need to, and try to avoid any Windows code on my machine at all possible. So, sorry Wine, your technology is very powerful and enabling, but I don't think I will be using you for the moment.